List of main publications Andreu, J. Bucharova, A; van Kleunen, M Introduction history and species characteristics partly explain naturalization success of North American woody species in Europe. The fungal dimension of biological invasions. Hulme PE Trade, transport and trouble:
But while breakthroughs like animal cloning, sequencing and synthesis of complete genomes have admirably demonstrated our capabilities in the field of biotechnology, we are still in the early stages when it comes to designing and prototyping complex Kiril alexandrov systems.
Professor Alexandrov is developing new methods for rapid in vitro synthesis and engineering of proteins and protein-based machines. He says that these methods are vital in biotechnology, as the ability to produce and analyse proteins determines the cost and speed of discovering and creating new diagnostic methods, vaccines and drugs.
A recent innovation involved the re-engineering of the enzyme used in blood glucose monitors, glucose dehydrogenase GDH. Using a device that simply plugs into a smartphone, it should become possible to perform a variety of molecular diagnostic tests rapidly and cheaply, anywhere, any time.
An estimated million people globally use some kind of smartphone app to help them manage their stress. This will make treatment and lifestyle management decisions for people who suffer from stress disorders far more personalised.
The perfect protein switch We are using a combination of protein design and directed evolution to create a switch Kiril alexandrov can be integrated in different proteins and enzymes and used to control their activity. This crates a new level of control in in vitro and in vivo proteins-based systems.
Electronic control of biochemical processes We are developing a novel approach that enables computers control chosen biochemical pathways with electric signals.
If successful, this will lead to better integration of biological and synthetic systems enabling biological augmentation and enhancement. Sense codon reassignment Proteins are composed predominately of 20 canonical amino acids that cover only a tiny segment of the available chemical space.
The genetic code can be potentially expanded to include chemistries not occurring in nature. We developed a novel approach for using the redundant sense codons for introducing unnatural amino acids into proteins Research projects A perfect protein switch We are using a combination of protein design and directed evolution to create a switch that can be integrated in different proteins and enzymes and used to control their activity.
This creates a new level of control in in vitro and in vivo proteins-based systems. Electronic control of biochemical processes. We are developing a novel approach that allows computers control chosen biochemical pathways with electric signals.
If successful, this will lead to better integration of biological and synthetic systems allowing biological augmentation and enhancement.
We developed a novel approach for using the redundant sense codons for introducing unnatural amino acids into proteins. Research training opportunities Research title: The exponential increase in the number of sequenced genomes has focused attention on how best to produce, study and modify the encoded gene products.
Accessing the information encoded in proteins is technically and economically challenging. This constitutes a critical technological bottleneck that determines the pace of progress in many areas of biology and biotechnology.
We are working on the approaches that allow rapid and flexible production, analysis and engineering of proteins and protein complexes. By integrating cell-free protein production, microfluidic handling and single molecule fluorescence spectroscopy, we develop new processes for understanding complex molecular machines such as tethering complexes and transcription regulating complexes.
Further, we use the developed technologies for construction of novel biological modules and cascades. Traineeships, honours and PhD projects include Quantitative analysis of protein-protein and protein-small molecule interactions using a novel in vitro translation system Development of approaches for recombinant production and biophysical analysis of multi-subunit protein complexes Development of high-yield eukaryotic protein expression systems based on protozoan Leishmania tarentolae Development of synthetic protein receptors and signal amplification cascades, and point-of-care diagnostic devices.View Kiril Alexandrov’s profile on LinkedIn, the world's largest professional community.
Kiril has 5 jobs listed on their profile. See the complete profile on LinkedIn and discover Kiril’s connections and jobs at similar heartoftexashop.com: Associate CG Artist at REDVERTEX. Alexandrov, Kirill, Goody, Roger, Waldmann, Herbert and Wu, Yaowen (). The study of Rab GTPase recycling using semi- synthetic prenylated proteins.
In Herbert Waldmann and Petra Janning (Ed.), Chemical biology: Learning through case studies (pp.
) Weinheim: Wiley-VCH. The Internal Macedonian Revolutionary Organization (IMRO; Bulgarian: Вътрешна Македонска Революционна Организация (ВМРО), Vatreshna Makedonska Revolyutsionna Organizatsiya (VMRO); Macedonian: Внатрешна Македонска Револуционерна Организација, Vnatrešna Makedonska Revolucionerna Organizacija) was a.
Professional Football Club Ludogorets Razgrad (Bulgarian: ПФК Лудогорец Разград), commonly known as Ludogorets Razgrad or simply Ludogorets, is a Bulgarian professional association football club in Razgrad, which currently competes in the First Professional Football League, the top-tier of the Bulgarian football league system.
Fontaine, Frank, Overman, Jeroen, Moustaqil, Mehdi, Mamidyala, Sreeman, Salim, Angela, Narasimhan, Kamesh, Prokoph, Nina, Robertson, Avril A. B., Lua, Linda, Alexandrov, Kirill, Koopman, Peter, Capon, Robert J., Sierecki, Emma, Gambin, Yann, Jauch, Ralf, Cooper, Matthew A., Zuegg, Johannes and Francois, Mathias () Small-molecule inhibitors of the SOX18 transcription factor.
Kirill Alexandrov, Krasnoyarsk, Russia. Log in or sign up to contact Kirill Alexandrov or find more of your friends.